In patients with chronic type 1 diabetes, transplanting of stem-cell-derived beta cells can potentially cure the disease, but patients have to commit to life-long immunosuppression to prevent rejection of the transplanted cells from rejection by the immune system. The Tang lab is currently investigating approaches to shield the transplanted cells from the immune systems using novel.
The Transplant and Stem Cell Immunobiology (TSI) Laboratory uses multiple research directions to answer complex questions about stem cell therapy, heart and lung transplantation, and cardiovascular disease. Our laboratory focuses on the immunogenicity of allogeneic stem cells, tissues, and organs, and is interested in designing methods to prevent immunological recognition and rejection of such.
In 2004 he joined the Neurology Department at the University of California, San Francisco. He is currently the John Bowes Distinguished Professor in Stem Cell and Tissue Biology and Founding Director of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF. Dr. Kriegstein’s own research focuses on the way in which neural stem and progenitor cells in the.
More than 2,000 UCSF physicians and staff work side-by-side with the dedicated employees of the San Francisco Department of Public Health. San Francisco Veterans Affairs Health Care System UCSF medical students, residents and fellows rotate through the VA which provides nearly one third of all of the University's medical training.
All students admitted to the Developmental and Stem Cell Biology Program are guaranteed a stipend to cover living expenses, plus payment of tuition and fees. To make the available funds go as far as possible, all students who are admitted will be considered for fellowships administered by the UCSF Graduate Division, a major source of support for incoming students.
Jeffrey Bluestone, PhD, is the A.W. and Mary Margaret Clausen Distinguished Professor of Metabolism and Endocrinology and is the Director of the Hormone Research Institute in the Diabetes Center. His research over the past 25 years has focused on understanding the basic processes that control T cell activation and immune tolerance in autoimmunity and organ transplantation. He and members of.
Matthias Hebrok, PhD is Hurlbut-Johnson Distinguished Professor in Diabetes Research and Director of the Diabetes Center at the University of California, San Francisco. He received his Diploma degree in Cell Biology from the Albert-Ludwigs University, performed his PhD thesis at the Max-Planck-Institute, and conducted his postdoctoral research at HHMI at Harvard University.
The optical clarity and accessibility of embryonic and larval zebrafish brains make them an ideal system for direct in vivo imaging of neural stem cell (NSC) behavior. Through individual NSC labeling and in vivo time-lapse imaging, we find that vertebrate radial glia (RG), the principal NSCs in the brain, predominantly undergo asymmetric cell division (ACD) to generate a “high Notch” self.
Third, we are looking at how exposure to young blood rejuvenates neural stem cell function, synaptic plasticity and cognitive function in the old brain. Ultimately, our goal is to elucidate cellular and molecular mechanisms that promote brain rejuvenation as a means by which to combat age-related neurodegeneration and cognitive dysfunction. In the news: Check out our latest work on Tet2 as.
Sonja Schrepfer, M.D., Ph.D., Professor of Surgery, founded the Transplant and Stem Cell Immunobiology (TSI) Lab in 2009 in Germany. In 2016, she joined the faculty of the Department of Surgery at the University of California San Francisco. She is also Director of the TSI Lab at UCSF.
The focus has been on the roles of morphogenic and developmental signaling pathways on the stem cell behavior, cell fate, migration and axon guidance during embryonic and postnatal development. In this area, previous work focused on the roles of Wnt, chemokines and BMP signaling pathways in the developing cortex. More recently, this work has focused on the role of the Sonic Hedgehog pathway in.
UCSF School of Dentistry is a leader in multidisciplinary scientific and clinical research, creating new knowledge and improving patient care Stuart Gansky Named Associate Dean for Research News story.